Glucose homeostasis and p75NTR

Glucose homeostasis and p75NTR

The p75 neurotrophin receptor (p75), a member of the tumor necrosis factor receptor (TNFR) superfamily, was originally identified as a receptor for neurotrophins and is expressed in the nervous system and in many non-neuronal tissues such as white adipose tissue (WAT), skeletal muscle and liver. Although the biological functions of p75 in the nervous system have been extensively studied, the mu...

Islets and Glucose Homeostasis

Copyright © 2015 Tien-Jyun Chang et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Diabetes mellitus is a chronic progressive metabolic disease, resulting from both insulin resistance and the dysfunction of beta-cells. Beta-c...

Bisphosphonates and glucose homeostasis

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Glucose Homeostasis – Mechanism and Defects

Glucose is an essential metabolic substrate of all mammalian cells. D-glucose is the major carbohydrate presented to the cell for energy production and many other anabolic requirements. Glucose and other monosaccharides are transported across the intestinal wall to the hepatic portal vein and then to liver cells and other tissues. There they are converted to fatty acids, amino acids, and glycog...

Sleeping, Waking, … and Glucose Homeostasis